Association of stiff-person syndrome with autoimmune endocrine diseases
نویسندگان
چکیده
منابع مشابه
Rhabdomyolysis and Autoimmune Variant Stiff-Person Syndrome
Stiff-person syndrome (SPS) is a rare neurologic disorder characterized by waxing and waning muscular rigidity, stiffness and spasms. Three subtypes have been described: paraneoplastic, autoimmune and idiopathic. Rhabdomyolysis has been described in the paraneoplastic variant, but to our knowledge no case has been reported involving the autoimmune variant. We report a case report of a 50-year-o...
متن کاملLatent autoimmune diabetes in Stiff-Person Syndrome.
GAD antibody (GADA) positivity is a hallmark of autoimmune diabetes and the rare autoimmune neurological disorder Stiff-Person Syndrome (SPS). Concomitant SPS and classical type 1 diabetes (T1D) have been described in case reports (1–3). A recent series of SPS reported the prevalence of T1D at 43% (4). However, the presence of alternative forms of autoimmune diabetes, such as latent autoimmune ...
متن کاملRigidity and spasms from autoimmune encephalomyelopathies: stiff-person syndrome.
Stiff-person syndrome (SPS) is a disorder characterized by progressive muscle rigidity with superimposed painful muscle spasms and gait impairment due to continuous motor activity. Evidence has accumulated in favor of SPS representing an autoimmune, predominantly encephalomyelopathic disorder resulting from B-cell-mediated clonal production of autoantibodies against presynaptic inhibitory epito...
متن کاملStiff Person Syndrome.
Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient of stiff person syndrome.
متن کاملStiff person syndrome.
Recognizing stiff person syndrome is clinically important. It is uncommon, characterized by body stiffness associated with painful muscle spasms, and varies in location and severity. It is subdivided into stiff trunk versus stiff limb presentation, and as a progressive encephalomyelitis. Stiff person-type syndrome also reflects a paraneoplastic picture. Most patients demonstrate exaggerated lum...
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ژورنال
عنوان ژورنال: World Journal of Clinical Cases
سال: 2019
ISSN: 2307-8960
DOI: 10.12998/wjcc.v7.i19.2942